M. Saio, R. Kushibiki, Y. Kanehira, A. Ishizawa, Y. Abe, S. Kobayashi, Y. Nishijima, Continuous specimen cooling during slicing and thickness measurement contributes to improved accuracy in image analysis of pathologic specimens. Histol. Histopathol. (2024) Epub ahead of print.
2023年
M. Ouchi, S. Kobayashi, Y. Nishijima, N. Inoue, H. Ikota, A. Iwase, H.
Yokoo, M. Saio, Decreased lamin A and B1 expression results in nuclear
enlargement in serous ovarian carcinoma, whereas lamin A-expressing tumor
cells metastasize to lymph nodes. Pathol Res Pract 247 (2023) 154560, 10.1016/j.prp.2023.154560.
2022年
Watabe S, Kobayashi S, Hatori M, Nishijima Y, Inoue N, Ikota H, Iwase A,
Yokoo H, Saio M: Role of Lamin A and emerin in maintaining nuclear morphology
in different subtypes of ovarian epithelial cancer. Oncol Lett 2022, 23:9.
Kimura K, Kanto T, Shimoda S, Harada K, Kimura M, Nishikawa K, Imamura
J, Ogawa E, Saio M, Ikura Y, Okusaka T, Inoue K, Ishikawa T, Ieiri I, Kishimoto
J, Todaka K, Kamisawa T: Safety, tolerability, and anti-fibrotic efficacy
of the CBP/beta-catenin inhibitor PRI-724 in patients with hepatitis C
and B virus-induced liver cirrhosis: An investigator-initiated, open-label,
non-randomised, multicentre, phase 1/2a study. EBioMedicine 2022, 80:104069.
Nishijima Y, Inoue N, Iwase A, Yokoo H, Saio M: MicroRNA 182, 183, 200a,
and 200b exhibit strong correlations but no involvement in PTEN protein
regulation in uterine endometrial carcinoma. Pathol Res Pract 2022, 236:153986.
Kimura M, Ogawa E, Harada K, Imamura J, Saio M, Ikura Y, Yatsuhashi H,
Murata K, Miura K, Ieiri I, Tanaka A, Kimura K: Feasibility, safety and
tolerability of the CREB-binding protein/beta-catenin inhibitor OP-724
in patients with advanced primary biliary cholangitis: an investigator-initiated,
open-label, non-randomised, two-centre, phase 1 study. BMJ Open Gastroenterol
2022, 9.
Mukade Y, Kobayashi S, Nishijima Y, Kimura K, Watanabe A, Ikota H, Shirabe
K, Yokoo H, Saio M: Phosphotungstic Acid-treated Picrosirius Red Staining
Improves Whole-slide Quantitative Analysis of Collagen in Histological
Specimens. J Histochem Cytochem 2022:221554221141140.
Hiroe T, Moriya S, Kobayashi S, Nishijima Y, Watanabe A, Shirabe K, Ikota
H, Yokoo H, Saio M: Negative correlation between the nuclear size and nuclear
Lamina component Lamin A in intraductal papillary mucinous neoplasms of
the pancreas. Pathol Oncol Res 2022, 28:1610684.
Tsedenbal B, Enebish G, Tserensodnom B, Saio M: Results of Self-Sampling
Methodology Impression for Cervical Cancer Screening in Mongolia. Asian
Pac J Cancer Prev 2022, 23:4099-107.
2021年
Takemori, N, Ooi, HK, Imai, G, Saio, M, Diverse effects of clarithromycin
and proposal of its clinical application for treating COVID-19 as a repurposing
drug, Trop Biomed, 2021, 38, 343-352.
Suzuki, M, Moriya, S, Kobayashi, S, Nishijima, Y, Fujii, T, Ikota, H, Yokoo,
H, Saio, M, Computer-assisted image analysis of cytological specimens clarify
the correlation between nuclear size and intranuclear cytoplasmic inclusions
regardless of BRAFV600E mutation in papillary thyroid carcinoma, Cytopathology,
2021,
.Nonaka, K, Saio, M, Umemura, N, Kikuchi, A, Takahashi, T, Osada, S, Yoshida, K, Th1 polarization in the tumor microenvironment upregulates the myeloid-derived suppressor-like function of macrophages, Cell Immunol, 2021, 369, 104437.
2020年
Kobayashi, S, Saio, M, Fujimori, M, Hirato, J, Oyama, T, Fukuda, T, Macrophages
in Giemsa-stained cerebrospinal fluid specimens predict carcinomatous meningitis,
Oncol Lett, 2020, 20, 352.
Fujimori, M, Tsuchihashi, H, Fujimori, S, Kobayashi, S, Nomi, Y, Hirato,
J, Oyama, T, Fukuda, T, Saio, M, High neutrophil incorporation rate of
ascitic fluid cytology as an indicator of cancerous ascites, Int J Oncol,
2020, 57, 1214-1222
Hatori, M, Moriya, S, Fujimori, Mら. Phosphomolybdic Acid Prevents Nonspecific
Nuclear Staining by Picrosirius Red but Is Converted to Molybdenum Blue
by Blue Light. J Histochem Cytochem 2020: 22155420942620.
Umemura, N, Sugimoto, M, Kitoh, Y, Saio, M, Sakagami, H, Metabolomic profiling
of tumor-infiltrating macrophages during tumor growth, Cancer Immunol Immunother,
2020, 69, 2357-2369.
Takemori N, Ooi H, Imai G, Hoshino K, Saio M: Possible mechanisms of action
of clarithromycin and its clinical application as a repurposing drug for
treating multiple myloma. ecancermedicalscience, 2020. pp. 1-24.
2019年
Kobayashi, S, Saio, M, Fukuda, Tら. Image analysis of the nuclear characteristics
of emerin protein and the correlation with nuclear grooves and intranuclear
cytoplasmic inclusions in lung adenocarcinoma. Oncol Rep 2019; 41: 133-142.
齊尾征直, 羽鳥瑞歩, 守谷駿一ら. パラフィンブロック冷却装置付きミクロトームと義歯安定剤のブロック裏面間隙充填による連続薄切への効果の検討. The Kitakanto Medical Journal 2019; 69: 1-6.
齊尾征直, 守谷駿一, 藤森美沙ら. パラフィンブロック薄切時持続冷却の標本の厚みに与える影響の画像解析による検討. The Kitakanto
Medical Journal 2019; 69: 97-104.
2018年
Tsedenbal, B, Yoshida, T, Enkhbat, Bら. Human papillomavirus genotyping
among women with cervical abnormalities in Ulaanbaatar, Mongolia. Int J
Infect Dis 2018; 77: 8-13.
Maruyama, N, Nishihara, K, Nakasone, Tら. Triple primary malignancies of
surface osteosarcoma of jaw, myelodysplastic syndrome and colorectal cancer
as a second primary cancer detected by PET2-[(18)F]-fluoro-2-deoxy-D-glucose
positron emission tomography: A case report. Oncol Lett 2018; 15: 9901-9907.
Taira, N, Kawasaki, H, Atsumi, Eら. Mucoepidermoid Carcinoma of Arising
from a Bronchogenic Cyst of the Diaphragm. Ann Thorac Cardiovasc Surg 2018;
24: 247-250.
齊尾征直. 細胞診断学の楽しさを伝えられる研究室を目指して. THE KITAKANTO MEDICAL JOURNAL 2018; 68:
69-70.
2017年
Kosuge, N, Saio, M, Matsumoto, Hら. Nuclear features of infiltrating urothelial
carcinoma are distinguished from low-grade noninvasive papillary urothelial
carcinoma by image analysis. Oncol Lett 2017; 14: 2715-2722.
Kimura, K, Ikoma, A, Shibakawa, Mら. Safety, Tolerability, and Preliminary
Efficacy of the Anti-Fibrotic Small Molecule PRI-724, a CBP/beta-Catenin
Inhibitor, in Patients with Hepatitis C Virus-related Cirrhosis: A Single-Center,
Open-Label, Dose Escalation Phase 1 Trial. EBioMedicine 2017; 23: 79-87.
Maruyama, T, Nishihara, K, Saio, Mら. Kikuchi-Fujimoto disease in the regional
lymph nodes with node metastasis in a patient with tongue cancer: A case
report and literature review. Oncol Lett 2017; 14: 257-263.
Wakayama, A, Matsumoto, H, Aoyama, Hら. Recurrent female adnexal tumor of
probable Wolffian origin treated with debulking surgery, imatinib and paclitaxel/carboplatin
combination chemotherapy: A case report. Oncol Lett 2017; 13: 3403-3408.
Matsuzaki, A, Saio, M, Kosuge, Nら. Primary Villoglandular Mucinous Adenocarcinoma
of the Vulva. Case Rep Pathol 2017; 2017: 1765460.
Taira, N, Kawasaki, H, Koja, Aら. Giant pedunclated lipoma of the esophagus:
A case report. Int J Surg Case Rep 2017; 30: 55-57.
学会での発表(筆頭が研究室内の場合,太文字)
2023
Saio M, Kobayashi S, Kanehira Y, Kushibiki R, Nishijima Y: Evaluation of nuclear feature of lung adenocarcinoma in HE specimens by computer-assisted image analysis. The 20th Korea-Japan Joint Meeting for Diagnostic Cytopathology. Gunsan Saemangeum Convention Center, Gunsan, Jeolla-do, Korea, 2023.
Nishijima Y, Kobayashi S, Saio M: Comparative analysis of cytology specimens
in endometrioid carcinoma cases with and without endometrial hyperplasia.
The 20th Korea-Japan Joint Meeting for Diagnostic Cytopathology. Gunsan
Saemangeum Convention Center, Gunsan, Jeolla-do, Korea, 2023.
Kobayashi S, Kanehira Y, Kushibiki R, Oi M, Nishijima Y, Saio M: Analysis
of Driver Mutation–specific MicroRNA in Lung Adenocarcinoma Cell Lines.
The 20th Korea-Japan Joint Meeting for Diagnostic Cytopathology. Gunsan
Saemangeum Convention Center, Gunsan, Jeolla-do, Korea, 2023.
Hatori M, Moriya S, Ikota H, Kobayashi S, Nishijima Y, Shirabe K, Yokoo
H, Kimura K, Saio M: Direct Analysis of Virtual Slide Scanner Data for
Liver Fibrosis is Correlated with Ishak Score. 32nd Congress of the ESP
and XXXIII International Congres of the IAP. Grasgow (Web), 2020.
Hiroe T, Moriya S, Kobayashi S, Nishijima Y, Watanabe A, Ikota H, Shirabe
K, Saio HYM: Nuclear protein lamin A and emerin expression is down regulated
in carcinoma originated from intraductal papillary mucinous neoplasm. 32nd
Congress of the ESP and XXXIII International Congres of the IAP. Grasgow
(Web), 2020.
Kobayashi S, Saio M, Fujimori M, Nishijima Y, Fukuda T: Total cell count
in cerebrospinal fluid giemsa staining cytological specimen by computer-assisted
image analysis. 32nd Congress of the ESP and XXXIII International Congres
of the IAP. Grasgow (Web), 2020.
Moriya S, HIroe T, Hatori M, Kobayashi S, Nishijima Y, Fujii T, Ikota H,
Shirabe K, Yokoo H, Saio M: BRAF V600E Mutation Negative Cases Tend to
Loose Lamin A Expression in Papillary Thyroid Carcinoma. 32nd Congress
of the ESP and XXXIII International Congres of the IAP. Grasgow (Web),
2020.
Nishijima Y, Kobayashi S, Saio M: Evaluation of PTEN protein expression
in normal endometrium and endometrioid carcinoma surgical specimens. 32nd
Congress of the ESP and XXXIII International Congres of the IAP. Grasgow
(Web), 2020.
Nomi, Y, Fujimori, S, Tsuchihashi, Hら. The clinical and cytological analysis
of cell-in-cell phenomenon in pleural effusion. 20th international Congress
of Cytology 2019; Best Poster Preentation
Kobayashi, S, Saio, M, Fujimori, Mら. Comparison of the Cell Number of Cerebrospinal
Spinal Fluid Papanicolaou and Giemsa Staining Cytological Specimens by
Image Analysis. The 18th Korea-Japan Joint Meeting for Diagnostic Cytopathology
2019;
Kobayashi, S, Saio, M, Fujimori, Mら. LEUKOCYTE CLASSIFICATION BY IMAGE
ANALYSIS FOR SPINAL FLUID GIEMSA STAINING CYTOLOGICAL SPECIMENS. 20th international
Congress of Cytology 2019;
Fujimori, M, Tsuchihashi, H, Fujimori, Sら. Analysis of Cell in Cell phenomenon
for Ascetic Fluid Cytology. 20th international Congress of Cytology 2019;
10.Fujimori, M, Tsuchihashi, H, Fujimori, Sら. Significance of Cell-in-Cell
Phenomena in Ascitic Fluid Cytology. The 18th Korea-Japan Joint Meeting
for Diagnostic Cytopathology 2019;